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but difficulty in transport and communications with the north meant its settlers were effectively independent of Charles Town as late as the governorship of Philip Ludwell; even then, the north was controlled through an appointed deputy governor.On December 7, 1710, the Lords Proprietors decided to separate the Province of North Carolina from Charles Town's government, although they continued to own and control both regions.The city lies just south of the geographical midpoint of South Carolina's coastline and is located on Charleston Harbor, an inlet of the Atlantic Ocean formed by the confluence of the Ashley and Cooper rivers.Charleston had an estimated population of 134,385 in 2016.

North Charleston blocks any expansion up the peninsula, and Mount Pleasant occupies the land directly east of the Cooper River.The Westo had made enemies of nearly every other tribe in the region, however, and the English turned on them in 1679.Destroying them by 1680, the settlers were able to use their improved relations with the Cusabo and other tribes to trade, recapture runaway slaves, and engage in slaving raids of Spanish-allied areas.Because the Carolina's Fundamental Constitutions was never ratified, however, Charles Town was never incorporated during the colonial period, with the British Crown disallowing the one attempt to do so in the 1720s.At the time of contact, the area was inhabited by the Cusabo Indians. The Charlestonians initially allied with the Westo, a slaving northern tribe that had grown powerful trading for guns with the colonists in Virginia.

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